What is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a sequence found within human gastric juice. It has become one of the most widely studied peptides in tissue-repair research due to its stability, well-characterised sequence, and the breadth of preclinical evidence available in the peer-reviewed literature.
Structural summary
- Sequence: GEPPPGKPADDAGLV (15 amino acids)
- Molecular weight: ~1419.5 g/mol
- Solubility: freely soluble in bacteriostatic water; stable at neutral pH.
- Storage: lyophilised form is stable at 4°C; reconstituted solutions are typically stored refrigerated and used within four weeks under laboratory research conditions.
Mechanism of action (research context)
BPC-157 is investigated primarily for its interactions with pathways associated with angiogenesis and connective-tissue repair. In preclinical models, published research has explored:
- Interaction with VEGF pathways, thought to support new microvascular formation.
- Modulation of nitric-oxide (NO) synthesis.
- Effects on growth-hormone receptor expression in fibroblast populations.
These findings are drawn from in-vitro and animal-model work and are cited here strictly for research context.
Common research applications
Laboratories exploring BPC-157 typically use it in models investigating:
- Soft-tissue repair (tendon, ligament, muscle)
- Gastrointestinal-lining integrity
- Vascular / angiogenic response
Handling and reconstitution
Peptovia Research supplies BPC-157 in lyophilised form. Standard laboratory reconstitution practice is to add bacteriostatic water to the vial slowly along the wall, gently swirl (never shake), and allow full dissolution before use.
Our reconstitution calculator can help you plan the exact working concentration you need for your protocol.
Compliance reminder
All products supplied by Peptovia Research are for laboratory research use only and are not for human or veterinary consumption, diagnosis, treatment or therapy.